HOW DOES CBD WORK?
HOW DOES CBD WORK?
TYPES OF CBD
Understanding that there are three types of CBD on the market will help you appreciate the confusion and difficulty if differentiating all of the brands. They are as follows:
- Isolate – this is least expensive CBD and is made in a lab with no other phytochemicals, cannabinoids and usually not even the hemp plant. This is how the pharmaceutical companies make Epidiolex and Sativex and all the other brands that are in gas stations and head shops.
- Broad Spectrum- CBD made from the hemp plant but without the legal amount of .03% Delta-9 THC. This is more expensive to make that the CBD Isolate as it has more of the other beneficial compounds found in the plant.
- Full Spectrum-CBD made from the hemp plant but with the legal amount of Delta-9THC. This is usually the most expensive form of CBD as it requires more specific extraction techniques. Science is leaning towards this form being the most effective as the small amount of THC has been shown to help with the absorption and bioavailability of the CBD and other cannabinoids.
HOW DOES CBD WORK
Scientists had an rough idea in the 1960’s with people experiencing a ‘high’ after smoking marijuana, that there must be receptors in our brain that pick up the chemical that was responsible for this. In the early 1990’s it was discovered that almost every cell and organ in our bodies had natural ‘chemical receptors’ that interacted with two different endocannabinoids (or internal cannabinoids) that we naturally make. These receptors are found in our Central and Peripheral Nervous Systems, our Endocrine System and our Immune System. This interwoven and intercommunicating biological network was soon called the Endocannabinoid System. Phytocannabinoids (those cannabinoids coming from plants) were soon found to also interact with those Endocannabinoid receptors in our bodies (1).
The receptors in the Central Nervous System are called CB1 Receptors and have a high affinity for Delta-9 THC, resulting in the subsequent psychoactive effects, or ‘high’ experienced by individuals. The remaining body systems have receptors that are called CB2 receptors and they play a key role in the health of those other systems. CBD specifically interacts with the CB2 receptors.
Since its discovery, the Endocannabinoid System has been studied quite extensively in the last decade. Scientists now understand that it plays a great role in our memory, sleep, pain, cognitive abilities, immune response, appetite, energy balance and metabolism, insulin balance, stress response and muscle spasms. One system pulls from the other during times of extreme need, ignoring the system with fewer needs. When all of these systems are out of balance or harmony, as like during cancer or Crohn’s Disease, then homeostasis – or a ‘rebalancing’ is what is needed to start feeling better. This is what is referred to as “ Endocannabinoid Deficiency Syndrome”(2), coined by researchers back in 2004. Each system needs a boost in differing amounts and that is what a Full-Spectrum CBD supplement added to our diets can provide us with.
What has been studied most recently are the ‘combined interactive effects’ of all of the chemicals contained in the Hemp plant. These other compounds are called Terpenes and Flavinoids. Terpenes provide all plants in nature with their odors, (like lavender and eucalyptus) while Flavinoids provide plants with their unique flavors (like basil and cilantro). What has amazed researchers is that when these 100’s of different compounds are combined with different cannabinoids like CBD, CBC, CBG and CBN and in differing ratios, a myriad of great effects is the result. This combined effect is referred to as the “entourage effect”, whereby the “Whole is greater than the sum of its Parts”. So engineering a Full-Spectrum cannabinoid profile with special attention given to all of the other hemp plant compounds, is at the forefront of the latest research into the health benefits of CBD.
MyHomeostasis actually discovered all of this over the last few years, just by listening to our amazing customer feedback and talking with our farmers. And with your continued feedback and our dedication to engineering the most unique CBD extracts in the world, we will always be at the forefront of this health care revolution!
1-Mackie K. Cannabinoid receptors: where they are and what they do. J Neuroendocrinol. 2008;20 Suppl 1:10-14. doi:10.1111/j.1365-2826.2008.01671.x.
2-Dr. Ethan Russo, MD, first proposed the theory of clinical endocannabinoid deficiency in 2004 in a study published in Neuro Endocrinology Letters